Module  Module Function Number of genes Regulator 1 M P S Z D C V St Regulator 2 M P S Z D C V St Regulator 3 M P S Z D C V St Regulator 4 M P S Z D C V St Regulator 5 M P S Z D C V St Regulator 6 Regulator 7 Regulator 8 Regulator 9
Module01 Homeostasis of metal ions and extracellular protein degradation 58
Module02 Multiple metabolism 361 FGSG_05399 0 0 0 1 0 0 0 FGSG_02083 0 1 1 1 1 0 0 0 FGSG_01173 1 0 1 1 1 0 0 0 FGSG_05604 0 0 1 0 0 0 0 0 FGSG_08626 0 0 1 0 0 0 0 0 FGSG_07928 FGSG_01350 FGSG_03538
Module03 Cell cycle and DNA processing 1391 FGSG_10384 1 0 1 1 1 0 1 0 FGSG_13746 1 0 1 1 1 0 FGSG_10716 1 1 1 1 1 1 1 0 FGSG_07116 1 0 0 0 0 0 0 0 FGSG_09308 0 0 0 0 0 0 0 FGSG_00584 FGSG_07368 FGSG_08892
Module04 Translation; protein synthesis and metabolism 309 FGSG_02608 0 0 1 0 0 0 0 0 FGSG_09410 1 0 0 0 0 0 0 FGSG_13314 0 0 1 0 0 0 0 0 FGSG_05604 0 0 1 0 0 0 0 0 FGSG_01366 0 0 1 0 0 0 0 0 FGSG_10286 FGSG_00584 FGSG_10517 FGSG_09464
Module05 Transport; detoxification and metabolism of lysine 229 FGSG_06071 1 1 1 0 0 1 1 0 FGSG_01327 0 0 0 1 1 0 0 0 FGSG_10429 1 0 0 0 0 0 0 0 FGSG_09565 0 1 0 0 0 0 0 0 FGSG_00568 0 0 0 0 0 0 0 FGSG_05381 FGSG_04220
Module06 Sphingolipid and polysaccharide metabolism; degradation of arginine 254 FGSG_08028 0 0 0 0 0 0 1 0 FGSG_06871 1 1 1 0 0 0 1 0 FGSG_01173 1 0 1 1 1 0 0 0 FGSG_05399 0 0 0 1 0 0 0 FGSG_02068 0 0 0 1 1 0 0 0 FGSG_00568 FGSG_01022
Module07 Metabolism of sulfuric acid and L-cysteine derivatives; meiosis I 186 FGSG_01366 0 0 1 0 0 0 0 0 FGSG_04220 1 0 1 1 1 0 1 0 FGSG_01366 0 0 1 0 0 0 0 0 FGSG_00750 1 0 0 1 1 0 0 1 FGSG_00404 0 0 1 0 0 0 0 0 FGSG_09339 FGSG_09992
Module08 Regulation of nucleotide/nucleoside/nucleobase metabolism 179 FGSG_04480 0 0 1 0 0 0 0 0 FGSG_08890 0 0 1 0 0 0 0 0 FGSG_10286 0 0 1 0 0 0 0 0 FGSG_07097 0 0 0 0 0 1 0 0 FGSG_02814 0 0 0 0 0 FGSG_10517
Module09 Detoxification, metabolism of toxins/drugs 405 FGSG_00902 0 1 0 1 0 1 0 1 FGSG_05399 0 0 0 1 0 0 0 FGSG_04480 0 0 1 0 0 0 0 0 FGSG_07928 1 0 1 0 0 0 1 0 FGSG_01173 1 0 1 1 1 0 0 0 FGSG_01366 FGSG_00750
Module10 Metabolism of aromate and about TCA and glyoxylate pathway; meiotic  287 FGSG_04220 1 0 1 1 1 0 1 0 FGSG_08481 1 0 1 1 1 1 1 FGSG_00385 1 1 1 1 1 1 1 FGSG_06944 1 0 1 0 0 0 1 0 FGSG_09308 0 0 0 0 0 0 0 FGSG_07928 FGSG_07546
Module11 Transport; degradation / modification of foreign polysaccharides 155 FGSG_01366 0 0 1 0 0 0 0 0 FGSG_08769 1 0 1 1 1 0 1 0 FGSG_03536 0 0 0 1 1 0 0 0 FGSG_01022 1 0 1 1 1 0 1 1 FGSG_07052 1 0 1 0 0 1 1 0 FGSG_10384 FGSG_08719
Module12 Metabolism of the cysteine - aromatic group; transport; secondary metabolism 168 FGSG_01327 0 0 0 1 1 0 0 0 FGSG_01366 0 0 1 0 0 0 0 0 FGSG_04220 1 0 1 1 1 0 1 0 FGSG_05381 0 0 0 0 0 0 0 1 FGSG_09308 0 0 0 0 0 0 0 FGSG_06160 FGSG_10517
Module13 Protein binding ; protein fate; transcription 729 FGSG_06382 0 0 1 0 0 0 0 0 FGSG_00902 0 1 0 1 0 1 0 1 FGSG_02814 0 0 0 0 0 FGSG_08617 1 0 1 1 1 0 1 0 FGSG_06071 1 1 1 0 0 1 1 0 FGSG_00750 FGSG_01915
Module14 rRNA and RNA processing; nucleic acid binding; transcription 303 FGSG_00324 1 1 1 0 1 1 1 FGSG_10429 1 0 0 0 0 0 0 0 FGSG_04134 1 1 1 1 1 1 1 0 FGSG_00568 0 0 0 0 0 0 0 FGSG_06701 0 0 1 0 0 0 0 0 FGSG_04220 FGSG_06810
Module15 Metabolism of amino acid; photoperception and response 272 FGSG_04220 1 0 1 1 1 0 1 0 FGSG_10384 1 0 1 1 1 0 1 0 FGSG_10429 1 0 0 0 0 0 0 0 FGSG_08719 1 0 1 1 1 1 1 1 FGSG_05171 1 1 1 1 1 0 1 1 FGSG_01327 FGSG_08892
Module16 Metabolism; anti-apoptosis; circulation; gas and metabolite distribution 80 FGSG_07928 1 0 1 0 0 0 1 0 FGSG_09019 1 0 1 1 1 0 1 0 FGSG_07052 1 0 1 0 0 1 1 0 FGSG_09000 0 0 1 0 0 0 0 0 FGSG_08892 0 0 1 0 0 0 0 0 FGSG_05068 FGSG_06944
Module17 Signal transduction mechanism; protein fate; chemical agent resistance  272 FGSG_01877 0 1 1 0 0 1 0 0 FGSG_02083 0 1 1 1 1 0 0 0 FGSG_00750 1 0 0 1 1 0 0 1 FGSG_04083 0 1 1 0 0 0 1 0 FGSG_03538 NA NA NA NA NA NA NA NA FGSG_09000 FGSG_06356
Module18 Electron transport and membrane-associated energy conservation 278 FGSG_04220 1 0 1 1 1 0 1 0 FGSG_10384 1 0 1 1 1 0 1 0 FGSG_00318 0 0 1 0 0 0 0 1 FGSG_08626 0 0 1 0 0 0 0 0 FGSG_06542 0 0 1 0 0 0 1 FGSG_02083 FGSG_01307
Module19 Multiple metabolism; transport; detoxification 124 FGSG_07157 1 0 1 0 0 0 0 FGSG_07052 1 0 1 0 0 1 1 0 FGSG_03538 NA NA NA NA NA NA NA NA FGSG_01915 1 0 0 1 0 0 FGSG_09019 1 0 1 1 1 0 1 0 FGSG_06651 FGSG_08626
Module20 Synthesis and replication; metabolism of secondary products  258 FGSG_00545 1 0 0 0 0 0 0 1 FGSG_00584 0 0 0 1 1 0 0 0 FGSG_05304 1 0 1 1 1 0 1 FGSG_05604 0 0 1 0 0 0 0 0 FGSG_07928 1 0 1 0 0 0 1 0 FGSG_02608 FGSG_06542 FGSG_03538 FGSG_00568
Module21 Protein fate; enzymatic activity regulation / enzyme regulator 542 FGSG_00574 1 1 0 0 0 1 1 FGSG_10429 1 0 0 0 0 0 0 0 FGSG_07075 1 0 0 0 0 0 0 1 FGSG_00930 1 1 1 1 1 0 0 1 FGSG_04901 1 0 0 0 0 0 0 0 FGSG_13746 FGSG_06701
Module22 Metabolism of urea cycle, creatine and polyamine; biosynthesis of lysine 222 FGSG_09308 0 0 0 0 0 0 0 FGSG_13314 0 0 1 0 0 0 0 0 FGSG_00318 0 0 1 0 0 0 0 1 FGSG_11799 1 0 0 0 0 0 0 1 FGSG_01022 1 0 1 1 1 0 1 1 FGSG_08626
Module23 Multiple metabolism; biotin binding 296 FGSG_04220 1 0 1 1 1 0 1 0 FGSG_06071 1 1 1 0 0 1 1 0 FGSG_07097 0 0 0 0 0 1 0 0 FGSG_06944 1 0 1 0 0 0 1 0 FGSG_05171 1 1 1 1 1 0 1 1 FGSG_10142 FGSG_08626 FGSG_02320
Module24 Nucleoside/nucleobase catabolism; tRNA and RNA modification 179 FGSG_08028 0 0 0 0 0 0 1 0 FGSG_13314 0 0 1 0 0 0 0 0 FGSG_00147 0 0 0 0 0 0 1 FGSG_00750 1 0 0 1 1 0 0 1 FGSG_09832 1 0 1 0 0 1 1 0 FGSG_04480 FGSG_03536 FGSG_12970
Module25 RNA topology; interleukine receptor signalling pathway 343 FGSG_06871 1 1 1 0 0 0 1 0 FGSG_01327 0 0 0 1 1 0 0 0 FGSG_00653 0 0 0 0 0 0 0 FGSG_05399 0 0 0 1 0 0 0 FGSG_02803 1 0 0 0 0 1 0 1 FGSG_01366 FGSG_09308
Module26 Complex cofactor binding; metabolism; electron transport; degradation  27 FGSG_12970 1 0 1 0 0 0 0 1 FGSG_01350 1 0 1 0 1 0 1 0 FGSG_01877 0 1 1 0 0 1 0 0 FGSG_07067 1 0 1 1 0 0 1 0 FGSG_01877 0 1 1 0 0 1 0 0 FGSG_06701 FGSG_12970
Module27 Virulence, disease and toxins factors; secondary metabolism 175 FGSG_01366 0 0 1 0 0 0 0 0 FGSG_04220 1 0 1 1 1 0 1 0 FGSG_04480 0 0 1 0 0 0 0 0 FGSG_06160 0 1 1 0 0 1 0 0 FGSG_10868 1 0 0 0 0 0 0 0 FGSG_06356 FGSG_13625 FGSG_10517
Module28 Heavy metal ion and siderophore-iron transport; homeostasis of cations 112 FGSG_09709 0 0 1 0 0 0 0 0 FGSG_09565 0 1 0 0 0 0 0 0 FGSG_10384 1 0 1 1 1 0 1 0 FGSG_01665 1 1 1 1 1 1 FGSG_13314 0 0 1 0 0 0 0 0 FGSG_00584 FGSG_02320
Module29 Regulation of channel activity; organ didderentiation; fungal organ 150 FGSG_05855 0 0 1 0 0 0 0 0 FGSG_06071 1 1 1 0 0 1 1 0 FGSG_00729 0 0 1 0 0 1 1 0 FGSG_09832 1 0 1 0 0 1 1 0 FGSG_05381 0 0 0 0 0 0 0 1 FGSG_13625 FGSG_10384 FGSG_08719
Module30 Multiple metabolism; respiration 373 FGSG_06356 0 0 0 0 0 0 0 FGSG_13314 0 0 1 0 0 0 0 0 FGSG_01173 1 0 1 1 1 0 0 0 FGSG_01176 0 0 1 1 1 0 1 FGSG_05604 0 0 1 0 0 0 0 0 FGSG_00318 FGSG_05475
Module31 C-compound and carbohydrate metabolism; disease; virulence and defense 286 FGSG_00545 1 0 0 0 0 0 0 1 FGSG_13314 0 0 1 0 0 0 0 0 FGSG_06427 0 0 1 0 0 0 1 0 FGSG_09709 0 0 1 0 0 0 0 0 FGSG_07052 1 0 1 0 0 1 1 0 FGSG_00318 FGSG_01350 FGSG_07052
Module32 Ribosomal proteins and ribosome biogenesis; translation; protein synthesis 79 FGSG_07116 1 0 0 0 0 0 0 0 FGSG_07052 1 0 1 0 0 1 1 0 FGSG_10179 0 0 0 0 0 0 1 1 FGSG_00584 0 0 0 1 1 0 0 0 FGSG_01915 1 0 0 1 0 0 FGSG_07133 FGSG_02719 FGSG_05068
Module33 Multiple metabolism; secondary metabolism 138 FGSG_09524 0 0 0 1 1 0 0 0 FGSG_07052 1 0 1 0 0 1 1 0 FGSG_00750 1 0 0 1 1 0 0 1 FGSG_07928 1 0 1 0 0 0 1 0 FGSG_09524 0 0 0 1 1 0 0 0 FGSG_08892 FGSG_04109
Module34 Unclassified prote ins 225 FGSG_01366 0 0 1 0 0 0 0 0 FGSG_00515 1 0 1 0 0 0 1 0 FGSG_00318 0 0 1 0 0 0 0 1 FGSG_08719 1 0 1 1 1 1 1 1 FGSG_02814 0 0 0 0 0 FGSG_02814 FGSG_04901
Module35 Transport ;assimilation of ammonia; metabolism of the glutamate group 323 FGSG_06291 1 1 1 1 1 1 1 FGSG_07097 0 0 0 0 0 1 0 0 FGSG_06944 1 0 1 0 0 0 1 0 FGSG_01665 1 1 1 1 1 1 FGSG_05381 0 0 0 0 0 0 0 1 FGSG_01915 FGSG_03536
Module36 Transport; lysosomal and vacuolar protein degradation 161 FGSG_01327 0 0 0 1 1 0 0 0 FGSG_05068 0 0 0 0 0 1 0 0 FGSG_04220 1 0 1 1 1 0 1 0 FGSG_00318 0 0 1 0 0 0 0 1 FGSG_00653 0 0 0 0 0 0 0 FGSG_01350 FGSG_10142
Module37 Multiple metabolism 118 FGSG_02083 0 1 1 1 1 0 0 0 FGSG_07157 1 0 1 0 0 0 0 FGSG_07052 1 0 1 0 0 1 1 0 FGSG_08626 0 0 1 0 0 0 0 0 FGSG_01576 0 0 1 0 0 0 0 0 FGSG_09524
Module38 Detoxification by export; resistance proteins 482 FGSG_08028 0 0 0 0 0 0 1 0 FGSG_01173 1 0 1 1 1 0 0 0 FGSG_04134 1 1 1 1 1 1 1 0 FGSG_05399 0 0 0 1 0 0 0 FGSG_13746 1 0 1 1 1 0 FGSG_05604 FGSG_00318 FGSG_07116
Module39 Cellular components; regulation of metabolism and protein function 460 FGSG_01106 0 0 1 1 1 0 1 0 FGSG_08626 0 0 1 0 0 0 0 0 FGSG_01341 0 0 1 0 0 1 1 FGSG_07097 0 0 0 0 0 1 0 0 FGSG_07097 0 0 0 0 0 1 0 0 FGSG_06651 FGSG_06356
Module40 Multiple metabolism; secondary metabolism; detoxification. 169 FGSG_02068 0 0 0 1 1 0 0 0 FGSG_06071 1 1 1 0 0 1 1 0 FGSG_01555 1 0 1 1 0 1 1 FGSG_09349 0 0 0 1 1 0 0 0 FGSG_04220 1 0 1 1 1 0 1 0 FGSG_00719 FGSG_08028 FGSG_02320
Module41 Metabolism; non-vesicular cellular import; energy 221 FGSG_13711 1 1 1 1 1 1 1 0 FGSG_01106 0 0 1 1 1 0 1 0 FGSG_09565 0 1 0 0 0 0 0 0 FGSG_05381 0 0 0 0 0 0 0 1 FGSG_10517 1 0 1 1 1 1 0 FGSG_02719 FGSG_05381
Module42 Anaerobic respiration; C- compound and organic acid catabolism; transport 245 FGSG_06356 0 0 0 0 0 0 0 FGSG_00750 1 0 0 1 1 0 0 1 FGSG_07116 1 0 0 0 0 0 0 0 FGSG_06701 0 0 1 0 0 0 0 0 FGSG_06701 0 0 1 0 0 0 0 0 FGSG_06701 FGSG_02320
Module43 Multiple metabolism; polysaccharide binding 110 FGSG_00729 0 0 1 0 0 1 1 0 FGSG_06160 0 1 1 0 0 1 0 0 FGSG_05399 0 0 0 1 0 0 0 FGSG_10868 1 0 0 0 0 0 0 0 FGSG_06160 0 1 1 0 0 1 0 0 FGSG_00573 FGSG_05475
Module44 Transport; regulation of action potential; sulfur and selenium metabolism 244 FGSG_04220 1 0 1 1 1 0 1 0 FGSG_08182 0 0 0 0 0 0 1 0 FGSG_06160 0 1 1 0 0 1 0 0 FGSG_07097 0 0 0 0 0 1 0 0 FGSG_00545 1 0 0 0 0 0 0 1 FGSG_10517
Module45 rRNA and RNA processing; transcription; RNA binding. 444 FGSG_06291 1 1 1 1 1 1 1 FGSG_04084 0 1 0 0 0 0 0 0 FGSG_09565 0 1 0 0 0 0 0 0 FGSG_05604 0 0 1 0 0 0 0 0 FGSG_11561 0 0 0 0 0 1 0 0 FGSG_00750 FGSG_08924 FGSG_03538
Module46 Secondary metabolism; detoxification involving cytochrome P; detoxification 44 FGSG_03538 NA NA NA NA NA NA NA NA FGSG_03536 0 0 0 1 1 0 0 0 FGSG_01350 1 0 1 0 1 0 1 0 FGSG_13314 0 0 1 0 0 0 0 0 FGSG_02814 0 0 0 0 0 FGSG_05855 FGSG_03538
Module47 Multiple metabolism; extracellular polysaccharide degradation 125 FGSG_13314 0 0 1 0 0 0 0 0 FGSG_00318 0 0 1 0 0 0 0 1 FGSG_09832 1 0 1 0 0 1 1 0 FGSG_09308 0 0 0 0 0 0 0 FGSG_01176 0 0 1 1 1 0 1 FGSG_06871 FGSG_02743 FGSG_13711
Module48 Sulfur metabolism 291 FGSG_11792 0 0 1 0 0 0 0 0 FGSG_05381 0 0 0 0 0 0 0 1 FGSG_04220 1 0 1 1 1 0 1 0 FGSG_05399 0 0 0 1 0 0 0 FGSG_10384 1 0 1 1 1 0 1 0 FGSG_01176 FGSG_07097
Module49 Translation; metabolism of neurotransmitters and organic acid 271 FGSG_05855 0 0 1 0 0 0 0 0 FGSG_08028 0 0 0 0 0 0 1 0 FGSG_00729 0 0 1 0 0 1 1 0 FGSG_06291 1 1 1 1 1 1 1 FGSG_01576 0 0 1 0 0 0 0 0 FGSG_05381 FGSG_00696 FGSG_09410
No effect Enhancement effect Weakening effect
total of 117 different regulators

We've got 49 modules due to ''Module networks'' modular processing, and each module contains its own regulators. After go enrichment, we got the function annotation of each module. Select the annotation function of the first 4 of the P value to integrate the functions of each module. As you can see, we have regulators included in each module, gene profiles included in each module, and the functions of each module we annotate. In addition, we have the phenotypic information of each regulator (Top 5 regulator of each module as an example). A total of 117 different regulators appear in the results of modularized networks, and we can count the frequency of these regulators and their corresponding impact phenotypes.

back

next